Abstract Despite the success of immune checkpoint blockade (ICB) therapy for esophageal squamous cell cancer, the key immune cell populations that affect ICB efficacy remain unclear.Here, imaging mass cytometry of tumor tissues from ICB-treated patients identifies a distinct cell population of CD39+PD-1+CD8+ T cells, specifically the TCF1+ subset,
A considerable market share of electric vehicles (EVs) is expected in the near future, which leads to a transformation from gas stations to EV charging infrastructure for automobiles.EV charging stations will be integrated with the power grid to replace the fuel consumption at the gas stations for the same telemarkskongen flue mobile needs.In order
Abstract Background Endometrial carcinosarcomas are rare and carry a very poor prognosis.They usually present with extensive lymphatic spread.An acute presentation of a stroke may reveal the underlying diagnosis.Case presentation A woman in her 50s with no reported medical history presented to the emergency department as a code stroke.She was found
In a thousands beds general hospital affiliated to the Tehran University, long-standing infestations of tillman 750m insects such as cockroaches, flies, mosquitoes and rat were found as a result of vicious circles and substandard clearing which are due to not well trained and drilled personnel of contracting agency, out of work condition of two inc